OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
a base insertion only.
|
|
|
a base deletion only.
|
|
|
a base substitution only.
|
|
|
either an insertion or a deletion of a base.
|
Detailed explanation-1: -A frameshift mutation in a gene refers to the insertion or deletion of nucleotide bases in numbers that are not multiples of three. This is important because a cell reads a gene’s code in groups of three bases when making a protein.
Detailed explanation-2: -Insertion frameshift mutation, wherein one or more nucleotides are added to the base sequence of the nucleic acid, which results in the change in the reading frame. The severity of this type of frameshift mutation is dependent on the number of nucleotides and the position of insertion of nucleotides.
Detailed explanation-3: -Thus a frameshift mutation (from either deletion or insertion) often results in a protein that is a different length than the original protein, with a new section of seemingly random amino acids attached to the end of the protein that have nothing to do with the sequence of amino acids that was there before.