LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Where are rRNA and tRNA made in the cell?
A
the nucleolus in the cytoplasm
B
the nucleolus in the mitochondria
C
the nucleolus in the nucleus
D
always in the cytoplasm
Explanation: 

Detailed explanation-1: -The most prominent substructure within the nucleus is the nucleolus (see Figure 8.1), which is the site of rRNA transcription and processing, and of ribosome assembly.

Detailed explanation-2: -The primary function of the nucleolus is in facilitating ribosome biogenesis, through the processing and assembly of rRNA into preribosomal particles.

Detailed explanation-3: -Ribosomal genes and RNA are transcribed in small regions of the nucleolus known as the ‘fibrillar center (FC)’ and ‘dense fibrillar component (DFC)’. The bulk of the nucleolus is the granular component (GC), where rRNA and proteins assemble to the ribosomal subunit (Figure 4).

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