LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
According to the induced fit model, as a substrate approaches an enzyme, it induces a ____ in the active site.
A
conformational change
B
chemical change
C
color change
D
None of the above
Explanation: 

Detailed explanation-1: -Since the induced fit theory tells that the substrate can actually induce a change in the active site of the enzyme, hence even if the inibitor attaches itself to the enzyme, the substrate can attach to it (by changing the shape of the active site).

Detailed explanation-2: -The binding of the substrate induces the enzyme to alter its shape fitting more tightly around the substrate.

Detailed explanation-3: -Substrates initially bind to the active site by noncovalent interactions, including hydrogen bonds, ionic bonds, and hydrophobic interactions. Once a substrate is bound to the active site of an enzyme, multiple mechanisms can accelerate its conversion to the product of the reaction.

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