OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction.
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The leading strand is synthesized at twice the rate of the lagging strand.
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The leading strand is synthesized in short fragments that are ultimately stitched together, whereas the lagging strand is synthesized continuously.
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The leading strand is synthesized by adding nucleotides to the 3’ end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5? end.
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Detailed explanation-1: -The leading strand is synthesized by adding nucleotides to the 3’ end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5’ end. The lagging strand is synthesized continuously, whereas the leading strand is synthesized in short fragments that are ultimately stitched together.
Detailed explanation-2: -Because the two strands of original or parental DNA run in opposite directions, the new strands must be made in different ways.
Detailed explanation-3: -Nucleotides of the leading strand are joined by the DNA polymerase. It only attaches at the 3’end of the growing strand. The fragments of the lagging strand are joined by DNA ligase. From the above information we have found that ‘DNA polymerase can join new nucleotides only to the 3’ end of the growing strand’.