LIFE SCIENCE

Detailed explanation-1: -Neutrophils are the first cell type recruited to sites of inflammation. From there, they can switch phenotypes and generate various subpopulations with different cell functions.

Detailed explanation-2: -Neutrophils are the first WBC population to arrive and affect the host inflammatory response during exercise and soft tissue injury ( Table). These cells have both specific and nonspecific defensive mechanisms, some of which are capable of causing additional tissue damage.

Detailed explanation-3: -Some of these attract neutrophils, which are the first cells recruited in large numbers to the site of the new infection. Others later attract monocytes and dendritic cells.

Detailed explanation-4: -Because neutrophils are the first type of leukocytes to arrive at affected tissues and display potent microbicidal functions, they have been classically viewed as the first line of defense. In this view, neutrophils only destroy invading pathogens and then quietly die at the site of infection.