OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Ig G
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Ig E
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Ig M
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Ig A
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Detailed explanation-1: -Immunoglobulin G (IgG), although it has a high molecular weight, is the only class of immunoglobulins able to cross the placenta and to reach the fetal circulation.
Detailed explanation-2: -IgG is the only antibody class that significantly crosses the human placenta.
Detailed explanation-3: -Introduction. Maternal immunoglobulin G (IgG) is transported across the placenta by an active, neonatal Fc receptor (FcRn) mediated process during pregnancy. This transport can confer short-term passive immunity1, 2, 3 and protect infants against infections during their first months of life.
Detailed explanation-4: -immunoglobulins-IgA and IgM are excluded from crossing the placenta. Thus IgM antibodies in the newborn indicate a response to intrauterine infection.