OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
primary mediators
|
|
|
secondary mediators
|
|
|
tertiary mediators
|
|
|
None of the above
|
Detailed explanation-1: -Leukotrienes are synthesized from the omega-6 polyunsaturated fatty acid arachidonic acid (AA), which is liberated intracellularly from membrane phospholipids by several phospholipase A2 enzymes (PLA2s), especially cytosolic PLA2 (cPLA2) (5).
Detailed explanation-2: -Summary – Prostaglandins vs Leukotrienes They are produced from 20-carbon polyunsaturated fatty acids called arachidonic acids. Prostaglandins are produced by all types of cells in our body. In contrast, leukotrienes are only produced by leukocytes.
Detailed explanation-3: -Secondary mediators include products of enzyme-dependent cascading biochemical pathways. In addition, secondary mediators may be derived from other involved cells, such as neutrophils, platelets, and eosinophils.