OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Mast cells mediate inflammatory responses such as hypersensitivity and allergic reactions.
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True
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False
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -Mast cells are now thought to exert critical proinflammatory functions, as well as potential immunoregulatory roles, in various immune disorders through the release of mediators such as histamine, leukotrienes, cytokines chemokines, and neutral proteases (chymase and tryptase).
Detailed explanation-2: -Mast cells are known for their main mechanism of action: IgE-mediated allergic reactions through the FcRI receptor. IgE antibodies are produced by mature B cells in response to CD4+ Th2 cells. Naïve mature B cells produce IgM and IgD antibodies. Once they become activated by an antigen, B cells will proliferate.
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