OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Production of antibodies and sensitized T-cells that attack and damage own tissue is characteristic of
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immunodeficiency
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auto-immune disease
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allergy hypersensitivity
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all of the above
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Explanation:
Detailed explanation-1: -A large body of human and murine studies has established multiple mechanisms by which T cell dysfunction promotes systemic autoimmunity in a variety of common rheumatic diseases including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), myositis, psoriasis/psoriatic arthritis, and vasculitis (15).
Detailed explanation-2: -T lymphocytes play a central role in regulation of the immune system. Both effector and regulatory T cells work in equilibrium to provide optimal immune response against foreign pathogens. Normally, T cells do not react against self-antigens because of the presence of central and peripheral immunogenic tolerance.
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