LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

SIGNALLING IMMUNOLOGY CANCER

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which dendritic cell is located in the liver?
A
Kupffer cells
B
Interdigitating Dendritic cells
C
Langerhans cells
D
Microglial cells
Explanation: 

Detailed explanation-1: -Among the hepatic immune cells, the hepatic dendritic cells (HDCs), uniquely, have a migratory capacity, produce particular cytokines and promote the adaptive immune system response and acts as a bridge between the innate and adaptive process (22).

Detailed explanation-2: -Kupffer cells are involved in the defence against infections of the liver. Their major role in the host defence and the prognosis of liver infection is indicated by studies in experimental models of sepsis.

Detailed explanation-3: -Development of an initial population of Kupffer cells begins in the embryonic yolk sac where precursor cells differentiate into fetal macrophages. Once they enter the blood stream, they migrate to the fetal liver where they stay. There they complete their differentiation into Kupffer cells.

There is 1 question to complete.