OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Somatic Hypermutation
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Class Switching to IgG
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Formation of Plasma Cells
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Formation of Germinal Center
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Detailed explanation-1: -T and B cells are activated when they recognize small components of antigens, called epitopes, presented by APCs, illustrated in Figure 2. Figure 2. An antigen is a macromolecule that reacts with components of the immune system.
Detailed explanation-2: -There are two main types of T-cells: Helper T-cells stimulate B-cells to make antibodies and help killer cells develop. Killer T-cells or cytotoxic T-cells directly kill cells that have already been infected by a foreign invader.
Detailed explanation-3: -For activation and differentiation into antibody-secreting plasma cells, mature B cells in the periphery lymphoid organs require two signals. The first signal is derived from antigen-coupled B cell receptors (BCRs), and the second signal can be delivered in a T cell-dependent (TD) or T cell-independent (TI) manner.