MEDICAL PHYSIOLOGY

Detailed explanation-1: -The great vessels of your heart have a wider lumen (opening) compared with your other arteries and veins. They need to be wider to accommodate the heavy volume of blood flow. Your aorta and pulmonary artery must also withstand forceful pressure from your heart’s pumping action.

Detailed explanation-2: -Arteries are more muscular and have smaller, rounder lumens (internal spaces) than veins. The artery lumen has a wavy endothelium, or inner lining, due to the configuration of elastic tissue beneath it.

Detailed explanation-3: -For example, the largest lumina in the human body are located in the intestines and aorta. Some examples of smaller lumina are ducts and channels traveling between organs including bile ducts, renal tubules, etc. The main characteristic of a lumen is its patency which means that it is open and unobstructed.