PHYSIOLOGY
ENDOCRINOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Decreased thyroid secretion greatly increases the plasma levels of cholesterol, phospholipids, and triglycerides
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TRUE
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FALSE
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -Thyroid hormone has a direct effect on cholesterol levels. Hypothyroid patients have increased cholesterol levels compared to individuals with normal thyroid function. Treatment with thyroid hormone often lowers the cholesterol levels in patients with hypothyroidism.
Detailed explanation-2: -Thyroid Hormone Reduces Cholesterol via a Non-LDL Receptor-Mediated Pathway-PMC.
Detailed explanation-3: -Thyroid hormone is known to play a role in regulating the synthesis, metabolism, and mobilization of lipids. In patients with overt hypothyroidism there is an increase in serum total cholesterol, low-density lipoprotein (LDL) cholesterol, apolipoprotein B, lipoprotein(a) levels, and possibly triglyceride levels.
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