PHYSIOLOGY
ENDOCRINOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Gold standard for diagnosing Growth Hormone deficiency
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Insulin Tolerance Test
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Arginine Stimulation Test
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Physical Activity Test
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75 g OGTT
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Explanation:
Detailed explanation-1: -The insulin stress test (IST) (or insulin tolerance test, ITT) has traditionally been the ‘gold standard’ test to assess the adequacy of the ACTH–adrenal axis. After adequate hypoglycaemia (blood glucose <2.2 mmol/L), a normal rise of plasma cortisol (traditionally to >550 nmol/L) excludes ACTH and cortisol deficiency.
Detailed explanation-2: -Macimorelin is indicated for diagnosis of adult growth hormone deficiency.
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