PHYSIOLOGY
ENDOCRINOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The basal membrane of the thyroid cell has the specific ability to pump the iodide actively to the interior of the cell
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Iodide trapping
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Iodine trapping
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Iodinization
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Deiodinization
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Explanation:
Detailed explanation-1: -The follicular cells have a very high concentration of iodide, and the entry of iodine into the cells is promoted by another hormone released from the pituitary gland – thyroid stimulating hormone (TSH).
Detailed explanation-2: -At first, inorganic iodide is actively concentrated by thyroid follicular cells by the sodium iodide symporter. Low iodide levels stimulate the intake of iodide via increased expression of the sodium iodide symporter.
Detailed explanation-3: -Pendrin, a 86-kDa chloride/iodide transport protein, is located at the apical membrane of thyrocytes, and is responsible for the transport of iodide ion into the follicular lumen.
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