PHYSIOLOGY
GENERAL PHYSIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Troponin
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Tropomyosin
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Myosin
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Actin
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Detailed explanation-1: -In addition to myosin that makes up the backbone of the thick filament, four other proteins which are intimately bound to the thick filament, myosin binding protein-C, titin, myomesin, and obscurin play important structural and regulatory roles.
Detailed explanation-2: -Organization of myosin thick filaments. Thick filaments are formed by the association of several hundred myosin II molecules in a staggered array. The globular heads of myosin bind actin, forming cross-bridges between the myosin and actin filaments.
Detailed explanation-3: -The bipolar thick filament is formed of approximately 300 myosin molecules and their associated proteins (Craig & Offer, 1976; Luther, Munro, & Squire, 1981). It has a strictly uniform dimension of 1.6 µm in length and 15 nm in diameter, which is independent of the type of muscle fiber (Huxley, 1963).