MEDICAL PHYSIOLOGY

PHYSIOLOGY

NEUROTRANSMISSION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The depletion of which of the following neurotransmitters is most closely associated with the symptoms of Alzheimer’s disease?
A
dopamine
B
acetylcholine (ACh)
C
serotonin
D
GABA
E
norepinephrine
Explanation: 

Detailed explanation-1: -Acetylcholine (ACh), a neurotransmitter essential for processing memory and learning, is decreased in both concentration and function in patients with Alzheimer’s disease.

Detailed explanation-2: -Levels of one neurotransmitter, acetylcholine, are particularly low in the brains of people with Alzheimer’s disease. Over time, different areas of the brain shrink.

Detailed explanation-3: -Two neurotransmitters seem to play a role in Alzheimer’s Disease: acetylcholine and glutamate.

Detailed explanation-4: -Alzheimer’s dementia is associated with the loss of cholinergic neurons that produce acetylcholine, but drugs that increase acetylcholine levels at the synapse don’t always result in significantly improved cognition.

Detailed explanation-5: -Not enough acetylcholine can lead to the loss of memory that’s seen in Alzheimer’s disease.

There is 1 question to complete.