MEDICAL PHYSIOLOGY

Detailed explanation-1: -The descending portion of the loop of Henle is extremely permeable to water and is less permeable to ions, therefore water is easily reabsorbed here and solutes are not readily reabsorbed.

Detailed explanation-2: -The Role of Aquaporins in the Kidneys The majority of water reabsorption that occurs in the nephron is facilitated by the AQPs. Most of the fluid that is filtered at the glomerulus is then reabsorbed in the proximal tubule and the descending limb of the loop of Henle.

Detailed explanation-3: -Ion transport along the nephron is essential for the reabsorption of sodium and water, maintenance of plasma volume, blood pressure and production of urine. The Loop of Henle contributes to the absorption of approximately 25% of filtered sodium and can be targeted by diuretic therapy.