MEDICAL PHYSIOLOGY

PHYSIOLOGY

SYNAPTIC PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Choose the steps for muscle relaxation
A
1. Acetylcholinesterase decomposes acetycholine, and the muscle fiber membrane is no longer stimulated. 2. Calcium ions are actively transported into the sarcoplasmic reticulum.3. ATP causes linkages between actin and myosin filaments to break without being broken down itself. 4. Troponin and tropomyosin interact, blocking binding sites on actin5. The muscle fiber relaxes.6. ATP breakdown “cocks” myosin cross-bridges. The musce fiber remains ready for further stimulation.
B
1. The muscle fiber relaxes. 2. Calcium ions are actively transported into the sarcoplasmic reticulum.3. Troponin and tropomyosin interact, blocking binding sites on actin4.ATP causes linkages between actin and myosin filaments to break without being broken down itself. 5. Acetylcholinesterase decomposes acetycholine, and the muscle fiber membrane is no longer stimulated. 6. ATP breakdown “cocks” myosin cross-bridges. The musce fiber remains ready for further stimulation.
C
1. Acetylcholinesterase decomposes acetycholine, and the muscle fiber membrane is no longer stimulated. 2. ATP breakdown “cocks” myosin cross-bridges. The musce fiber remains ready for further stimulation.3.Calcium ions are actively transported into the sarcoplasmic reticulum.4. ATP causes linkages between actin and myosin filaments to break without being broken down itself. 5. Troponin and tropomyosin interact, blocking binding sites on actin6. The muscle fiber relaxes.
D
1 ____ ATP breakdown “cocks” myosin cross-bridges. The muscle fiber remains ready for further stimulation.2.Calcium ions are actively transported into the sarcoplasmic reticulum.3.Acetylcholinesterase decomposes acetycholine, and the muscle fiber membrane is no longer stimulated. 4. ATP causes linkages between actin and myosin filaments to break without being broken down itself. 5. Troponin and tropomyosin interact, blocking binding sites on actin6. The muscle fiber relaxes.
Explanation: 

Detailed explanation-1: -Relaxing skeletal muscle fibers, and ultimately, the skeletal muscle, begins with the motor neuron, which stops releasing its chemical signal, ACh, into the synapse at the NMJ. The muscle fiber will repolarize, which closes the gates in the SR where Ca++ was being released.

Detailed explanation-2: -Ca++ pumped back in sarcoplasmic reticulum. release of Ca++ from troponin. cessation of interaction between actin and myosin.

Detailed explanation-3: -AChE decomposes ACh and the muscle fiber membrane is no longer stimulated. Potassium ions leave the muscle cell causing repolarization. Calcium ions are actively transported back into the sarcoplasmic reticulum. Linkages between actin and myosin filaments break. Actin and myosin filaments slide apart. More items

Detailed explanation-4: -Excitation. The process which the nerve fiber stimulates the muscle fiber (leading to generation of action potentials in the muscle cell membrane) Excitation-contraction coupling. Contraction. Relaxation.

There is 1 question to complete.