MEDICAL PHYSIOLOGY

Detailed explanation-1: -The absolute refractory period is a period of time after the initiation of one action potential when it is impossible to initiate a second action potential no matter how much the cell is depolarized.

Detailed explanation-2: -: the period immediately following the firing of a nerve fiber when it cannot be stimulated no matter how great a stimulus is applied.

Detailed explanation-3: -In summary, the absolute refractory period is when a neuron can no longer send an action potential. During an action potential, voltage-gated sodium channels open, and sodium rushes into the cell. After a specific period of time, the sodium channels slam shut and no longer let sodium in.

Detailed explanation-4: -In physiology, a refractory period is a period of time during which an organ or cell is incapable of repeating a particular action, or (more precisely) the amount of time it takes for an excitable membrane to be ready for a second stimulus once it returns to its resting state following an excitation.

Detailed explanation-5: -Absolute: Is the period of time during which a second action potential ABSOLUTELY cannot be initiated, no matter how large the applied stimulus is. Relative: Is the interval immediately following the Absolute Refractory Period during which initiation of a second action potential is INHIBITED, but not impossible.