MEDICAL PHYSIOLOGY

PHYSIOLOGY

SYNAPTIC PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
For a neuron with a resting membrane potential at-70mv, an increase in the movement of sodium ions into the neuron’s cytoplasm would result in:
A
the depolarization of the neuron.
B
the repolarization of the neuron
C
the replacement of potassium ions with sodium ions.
D
the replacement of potassium ions with calcium ions.
Explanation: 

Detailed explanation-1: -The resting membrane potential of a neuron is about-70 mV (mV=millivolt)-this means that the inside of the neuron is 70 mV less than the outside. At rest, there are relatively more sodium ions outside the neuron and more potassium ions inside that neuron.

Detailed explanation-2: -Resting membrane potential of a neuron is about-70mV which means that the inside of the neuron is 70mV less than the outside. There are more k and less NA+ inside and more NA+ and less K+ outside.

Detailed explanation-3: -The Sodium/Potassium Pump (ATPase) is responsible for maintaining the membrane potential at-70mv, the protein actively pumps three sodium ions out of the cell and pumps two potassium ions into the cell. The neurone becomes stimulated.

Detailed explanation-4: -If the membrane potential drops to below the normal resting state of-70mV, the neuron is hyperpolarized. Cells do not stay in a state of electrochemical neutrality because there is an uneven distribution of ions across a cell membrane.

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