MEDICAL PHYSIOLOGY

PHYSIOLOGY

SYNAPTIC PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why is penicillin not used in the treatment of human immunodeficiency virus (HIV)?
A
HIV patients may be allergic to penicillin.
B
Penicillin causes antibiotic resistance.
C
Penicillin can prevent phagocytes from functioning
D
Viruses have no metabolism of their own
Explanation: 

Detailed explanation-1: -HIV is a viral rather than bacterial disease, so antibiotics cannot be used to treat it directly.

Detailed explanation-2: -Viruses and bacteria also have a different structure and a different way of surviving. Viruses are surrounded by a protective protein coating; they don’t have cell walls that can be attacked by antibiotics like bacteria does. It is because of this that antibiotics don’t work on viruses.

Detailed explanation-3: -How does HIV attack the immune system? It binding to the protein CD4 allows the HIV to destroy the CD4+ immune system cells including helper T-cells and macrophages, and eventually stops the development of an immune response by eliminating helper T cells.

Detailed explanation-4: -The most important mechanism of resistance to penicillins and cephalosporins is -lactamase mediated hydrolysis of the -lactam ring, resulting in inactivation of the antibiotic.

There is 1 question to complete.