NEET BIOLOGY

Detailed explanation-1: -The first confirmed oncogene was discovered in 1970 and was termed SRC (pronounced “sarc” as it is short for sarcoma). SRC was first discovered as an oncogene in a chicken retrovirus. Experiments performed by Dr. G.

Detailed explanation-2: -The first infectious source of cancer was discovered in 1911, when a virus was first associated with cancer in chickens. Frances Peyton Rous, a virologist at Rockefeller Institute for Medical Research, transferred bacteria-free and cell-free extracts from a chicken with a lump in its breast to a healthy chicken.

Detailed explanation-3: -The first oncogenic human virus, Epstein–Barr virus, was observed in 1964 (Epstein et al., 1964) and causes Burkitt’s lymphoma. Kaposi’s sarcoma herpes virus was discovered in 1994 as the causal agent for Kaposi’s sarcoma (Chang et al., 1994), a disease frequently found in patients with HIV-associated AIDS.

Detailed explanation-4: -EBV was the first human oncogenic virus discovered, and was originally identified in Burkitt lymphoma cells in 1964 [1, 36].