NEET BIOLOGY

BIOLOGICAL CLASSIFICATION

VIRUSES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What are prions?
A
tiny circular molecules of RNA that can infect plants
B
misfolded versions of normal proteins that can causes disease
C
viral DNA that attaches itself to the host cell genome and cause disease
D
mobile segments of DNA
Explanation: 

Detailed explanation-1: -A prion /ˈpriːɒn/ ( listen) is a misfolded protein that can transmit its misfolded shape onto normal variants of the same protein. Prions are the causative agent of several transmissible and fatal neurodegenerative diseases in humans and other animals.

Detailed explanation-2: -Transmissible spongiform encephalopathies (TSEs or prion diseases) are a rare group of invariably fatal neurodegenerative disorders that affect humans and other mammals. TSEs are protein misfolding diseases that involve the accumulation of an abnormally aggregated form of the normal host prion protein (PrP).

Detailed explanation-3: -Although they start out as harmless brain proteins, when prions become misfolded, they turn into contagious pathogens that recruit any other prions they come into contact with, grouping together in clumps that damage other cells and eventually cause the brain itself to break down.

Detailed explanation-4: -A prion is a type of protein that can trigger normal proteins in the brain to fold abnormally. Prion diseases can affect both humans and animals and are sometimes spread to humans by infected meat products. The most common form of prion disease that affects humans is Creutzfeldt-Jakob disease (CJD).

Detailed explanation-5: -Creutzfeldt-Jakob disease (CJD) is caused by an abnormal infectious protein in the brain called a prion.

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