NEET BIOLOGY

Detailed explanation-1: -During interphase (1), chromatin is in its least condensed state and appears loosely distributed throughout the nucleus. Chromatin condensation begins during prophase (2) and chromosomes become visible. Chromosomes remain condensed throughout the various stages of mitosis (2-5).

Detailed explanation-2: -Consequently, during interphase, DNA is combined with proteins and organized into a precise, compact structure, a dense string-like fiber called chromatin, which condenses even further into chromosomes during cell division.

Detailed explanation-3: -During S phase of the eukaryotic cell division cycle, newly replicated DNA is rapidly assembled into chromatin. Newly synthesised histones form complexes with chromatin assembly factors, mediating their deposition onto nascent DNA and their assembly into nucleosomes.

Detailed explanation-4: -During interphase the DNA strands are uncoiled (uncondensed) in the nucleus. This uncondensed genetic material is called chromatin; thus an uncondensed chromosome can be called chromatin.

Detailed explanation-5: -In G1 phase, CHO xrs-5 cells were slightly more resistant to radiation than when in mitosis, but a significant proportion of their chromatin was found to remain in condensed form adjacent to the nuclear membrane.