NEET BIOLOGY

CELL STRUCTURES AND FUNCTION

CELL CYCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What would be the result of a mutation that allows a cell to move past checkpoint G2 even though DNA replication has not been completed?
A
The daughter cell would be small and possibly not able to store enough nutrients within the cell to survive. It can also cause cancer.
B
The DNA in the daughter cells would not be able to complete and the cells would not survive.
C
The chromosomes might end up in the wrong daughter cell. For example, one cell might get both copies of chromosomes while the other gets none.
D
None of the above
Explanation: 

Detailed explanation-1: -Predict the result of a mutation that allows a cell to move past checkpoint G2 even though the DNA replication has not been completed. the DNA in the daughter cells would not be complete and the cells would not survive.

Detailed explanation-2: -G2 checkpoint – DNA quality control After the second growth phase, the cell checks that the DNA was completely and correctly replicated during the S phase. If it passes it enters the M phase, and if it fails it tries to correct the errors. If the cell is unable to repair the DNA, it undergoes apoptosis.

Detailed explanation-3: -If the cell cycle checkpoints fail, cells that are not replicating correctly will be allowed to continue to grow and multiply. This is dangerous because the cell cycle mutations that are causing the failure can be passed on through the cell lineage.

Detailed explanation-4: -Which mutation would allow the cell to pass the G1 checkpoint when it should not? A mutation in Rb, preventing it from associating with E2F.

Detailed explanation-5: -If errors or damage are detected, the cell will pause at the G 2start subscript, 2, end subscript checkpoint to allow for repairs. If the checkpoint mechanisms detect problems with the DNA, the cell cycle is halted, and the cell attempts to either complete DNA replication or repair the damaged DNA.

There is 1 question to complete.