NEET BIOLOGY

Detailed explanation-1: -A gene variant is a permanent change in the DNA sequence that makes up a gene. This type of genetic change used to be known as a gene mutation, but because changes in DNA do not always cause disease, it is thought that gene variant is a more accurate term.

Detailed explanation-2: -There are three types of DNA Mutations: base substitutions, deletions and insertions. Single base substitutions are called point mutations, recall the point mutation Glu—–> Val which causes sickle-cell disease. Point mutations are the most common type of mutation and there are two types.

Detailed explanation-3: -Mutation is a process that causes a permanent change in a DNA sequence. Changes to a gene’s DNA sequence, called mutations, can change the amino acid sequence of the protein it codes for-but they don’t always. A point mutation is a change to single DNA letter.

Detailed explanation-4: -Mutations can be of many types, such as substitution, deletion, insertion, and translocation.