NEET BIOLOGY

GENETICS AND EVOLUTION

GENETIC BASIS OF INHERITANCE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In an AD inheritance pattern, affected individuals would have which of the following genotypes?
A
AA or Aa
B
aa
C
AA only
D
Aa only
Explanation: 

Detailed explanation-1: -A = dominant. a = recessive. AA-homozygous dominant. Aa-heterozygous dominant (individual has both dominant and recessive gene, but only one is expressed) Was this answer helpful?

Detailed explanation-2: -Individuals with genotypes AA and aa are homozygotes (i.e., they have two copies of the same allele).

Detailed explanation-3: -Genotype AA is the universally compatible genotype that is, regardless of who they partner up with, there is no possibility of them birthing a child with sickle cell disease. Here are the compatible and incompatible genotypes: AA + AA = compatible. AA + AS = compatible. AA + SS = compatible.

Detailed explanation-4: -The remaining half will inherit 2 recessive alleles (aa) and develop the disease. It is likely that every one of us is a carrier for a large number of recessive alleles. Some of these alleles can cause life-threatening defects if they are inherited from both parents.

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