NEET BIOLOGY

Detailed explanation-1: -In X-linked recessive inheritance, a daughter inherits a single mutated gene on the X chromosome from one of her parents. The X chromosome she inherits from the other parent will usually cancel the effect of the mutation, and she most likely will not have the genetic condition.

Detailed explanation-2: -Females can get an X-linked recessive disorder, but this is very rare. An abnormal gene on the X chromosome from each parent would be required, since a female has two X chromosomes.

Detailed explanation-3: -A male who has an X-linked recessive condition will always pass on the changed gene to his daughter, who will then be a carrier. However, if he has an X-linked dominant condition his daughter will be affected.

Detailed explanation-4: -A female with Turner syndrome will only have one X and will therefore express “X-linked recessive” conditions just as a male would. A female with an ‘XXX’ genotype may have a different X-inactivation pattern. A male with an ‘XXY’ genotype may express milder phenotype due to his X-inactivation pattern.

Detailed explanation-5: -Females (who have two X chromosomes) must have a mutation on both X chromosomes in order to be affected with the condition.