GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A + T = G + C
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the ratio of A to G is close to 1:1 and the ratio of T to C is close to 1:1
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the ratio of A to T is close to 1:1 and the ratio of G to C is close to 1:1
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A + T = 50% of the total bases
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Detailed explanation-1: -Chargaff’s rules state that DNA from any cell of all organisms should have a 1:1 ratio of pyrimidine and purine bases and, more specifically, that the amount of guanine is equal to cytosine and the amount of adenine is equal to thymine. This pattern is found in both strands of the DNA. Was this answer helpful?
Detailed explanation-2: -Chargaff rule: The rule that in DNA there is always equality in quantity between the bases A and T and between the bases G and C. (A is adenine, T is thymine, G is guanine, and C is cytosine.) Named for the great Austrian-American biochemist Erwin Chargaff (1905-2002) at Columbia University who discovered this rule.
Detailed explanation-3: -Chargaff’s rules state that in the DNA of any species and any organism, the amount of guanine should be equal to the amount of cytosine and the amount of adenine should be equal to the amount of thymine. Further a 1:1 stoichiometric ratio of purine and pyrimidine bases (i.e., A+G=T+C ) should exist.
Detailed explanation-4: -Rule 2. In 1947 Chargaff showed that the composition of DNA, in terms of the relative amounts of the A, C, G and T bases, varied from one species to another. This molecular diversity added evidence that DNA could be the genetic material.
Detailed explanation-5: -Chargaff’s rule 2 is that the composition of DNA varied from one species to another. The base paring rules state that A always pairs with T and G always pairs with C.