GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Meselson & Stahl
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Griffith
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Hershey & Chase
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Chargaff
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Detailed explanation-1: -By 1957, three theories about DNA replication prevailed: semi-conservative, conservative, and dispersive replication. Then, Matthew Meselson and Franklin Stahl conducted the Meselson-Stahl experiment, which returned results that supported the semi-conservative theory of DNA replication.
Detailed explanation-2: -The semiconservative mode of DNA replication was originally documented through the classic density labeling experiments of Matthew Meselson and Franklin W. Stahl, as communicated to PNAS by Max Delbrück in May 1958.
Detailed explanation-3: -Meselson & Stahl reasoned that these experiments showed that DNA replication was semi-conservative: the DNA strands separate and each makes a copy of itself, so that each daughter molecule comprises one “old” and one “new” strand.
Detailed explanation-4: -The Meselson Stahl Experiment. A centrifuge was used to separate DNA molecules labeled with isotopes of different densities. This experiment revealed a pattern that supports the semiconservative model of DNA replication.