GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The lagging strand towards replication fork.
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The leading strand away from replication fork.
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The lagging strand away from the replication fork.
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The leading strand towards replication fork.
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Detailed explanation-1: -The discontinuously synthesised fragments are called Okazaki fragments. Okazaki fragments are formed on the lagging strand away from the replication fork and later joined by the enzyme DNA ligase .
Detailed explanation-2: -Therefore, Okazaki fragments are used to elongate lagging strand away from the replication fork.
Detailed explanation-3: -Okazaki fragments are short sections of DNA formed at the time of discontinuous synthesis of the lagging strand during replication of DNA. It is essential as it allows for the synthesis of both the daughter strands required for cell division.
Detailed explanation-4: -The strand which is synthesized in 3’-5’ direction is the leading strand and the strand which is synthesized in the opposite direction is the lagging strand which contains the Okazaki fragments. This strand is synthesized away from the replication fork.
Detailed explanation-5: -The continuously synthesized strand is called the leading strand, since its elongation in the direction of replication fork movement exposes the template used for the synthesis of Okazaki fragments (the lagging strand).