NEET BIOLOGY

GENETICS AND EVOLUTION

MOLECULAR BASIS OF INHERITANCE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
On the lagging strand in replication, the Okazaki fragments must be joined by which enzyme?
A
DNA polymerase
B
primase
C
ligase
D
helicase
Explanation: 

Detailed explanation-1: -During lagging strand synthesis, DNA ligase I connects the Okazaki fragments, following replacement of the RNA primers with DNA nucleotides by DNA polymerase .

Detailed explanation-2: -The last deoxyribonucleotide is joined by a different enzyme, DNA ligase, which uses one ATP to join the Okazaki fragment into the growing lagging strand.

Detailed explanation-3: -Okazaki segments are joined by DNA ligase.

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