NEET BIOLOGY

GENETICS AND EVOLUTION

MOLECULAR BASIS OF INHERITANCE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
RNA primase is used show where DNA polymerase III is to attach to add nucleotides on the exposed lagging strand. What is the name of the promoter strand on the DNA lagging strand called?
A
telomere
B
TATA box
C
primer
D
topoisomerase
Explanation: 

Detailed explanation-1: -Helicase, primase, and two molecules of DNA polymerase III carry out coordinated synthesis of both the leading and lagging strands of DNA.

Detailed explanation-2: -Primase synthesizes RNA primers complementary to the DNA strand. DNA polymerase III extends the primers, adding on to the 3’ end, to make the bulk of the new DNA.

Detailed explanation-3: -For example, DNA polymerase III does most of the elongation work, adding nucleotides one by one to the 3’ end of the new and growing single strand.

Detailed explanation-4: -These primers serve as a starting point for DNA synthesis. Since primase produces RNA molecules, the enzyme is a type of RNA polymerase. Primase functions by synthesizing short RNA sequences that are complementary to a single-stranded piece of DNA, which serves as its template.

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