NEET BIOLOGY

Detailed explanation-1: -The three post-transcriptional modifications are as follows: Splicing: This involves the removal of the part of the gene that does not code for any protein (introns) and joining all the coding genes (exons) to form a functional gene.

Detailed explanation-2: -Post-transcriptional modifications of pre-mRNA, such as capping, splicing, and polyadenylation, take place in the nucleus. After these modifications have been completed, the mature mRNA molecules have to be translocated into the cytoplasm, where protein synthesis occurs.

Detailed explanation-3: -RNA splicing, the first stage of post-transcriptional control. In eukaryotic cells, the RNA transcript often contains regions, called introns, that are removed prior to translation.

Detailed explanation-4: -This process includes three major steps that significantly modify the chemical structure of the RNA molecule: the addition of a 5’ cap, the addition of a 3’ polyadenylated tail, and RNA splicing.

Detailed explanation-5: -Splicing occurs in the nucleus before the RNA migrates to the cytoplasm. Once splicing is complete, the mature mRNA (containing uninterrupted coding information), is transported to the cytoplasm where ribosomes translate the mRNA into protein. The pre-mRNA transcript contains both introns and exons.