GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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RNA primase
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single-strand binding proteins
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DNA polymerase I
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DNA ligase
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Detailed explanation-1: -DNA Helicases-These proteins bind to the double stranded DNA and stimulate the separation of the two strands.
Detailed explanation-2: -Proteins called Binding Proteins keep the two DNA strands apart preserving the Replication Fork.
Detailed explanation-3: -To unwind DNA, helicase first binds to DNA and then cleaves the hydrogen bonds connecting base pairs to separate the strands of the helix. Then single-stranded binding protein attaches to the single-stranded DNA. Helicase unwinds the DNA helix and SSB protein keeps the strands apart.
Detailed explanation-4: -Small molecules called single-stranded binding proteins (SSB) attach to the loose strands of DNA to keep them from re-forming the hydrogen bonds that helicase just broke apart. Figure 5.4. 2 Helicase unwinds and unzips the DNA molecule. SSB keep the two strands from re-attaching to one another.
Detailed explanation-5: -Figure 9.4 General Overview of a DNA Replication Fork. Two replication forks are formed by the opening of the double-stranded DNA at the origin, and helicase separates the DNA strands, which are coated by single-stranded binding proteins to keep the strands separated. DNA replication occurs in both directions.