GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Helicase
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Topoisomerase
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Ligase
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Hexokinase
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Detailed explanation-1: -Final answer: DNA Ligase is not involved during DNA replication on the template with polarity 3’ → 5’.
Detailed explanation-2: -DNA replication requires other enzymes in addition to DNA polymerase, including DNA primase, DNA helicase, DNA ligase, and topoisomerase.
Detailed explanation-3: -Helicase (separate double-stranded DNA into single strands allowing each strand to be copied) DNA gyrase (reduces supercoiling which builds up during DNA unwinding) DNA ligase (Joins the discontinuously synthesized fragments)
Detailed explanation-4: -The order of enzymes in DNA replication include the following: DNA helicase, RNA primase, DNA polymerase, and finally DNA ligase. During the process of DNA replication, the double helix unwinds with the help of the enzyme DNA helicase.