NEET PG DENTAL EXAM

BRAIN

MIDBRAIN

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Purkinje cells are ____, while cerebellar nuclei are ____
A
excitatory, excitatory
B
inhibitory, inhibitory
C
excitatory, inhibitory
D
inhibitory, excitatory
Explanation: 

Detailed explanation-1: -All cells in the cerebellar cortex are inhibitory except granule cells and unipolar brush cells (not shown). The cerebellar cortex receives two excitatory inputs from mossy fibers (MF) originating in various brain stem and spinal cord nuclei and from climbing fibers (CF) originating from the inferior olive (IO).

Detailed explanation-2: -Cerebellar Purkinje cells are known to receive strong excitatory input from two major pathways originating outside the cerebellum and inhibitory input from two types of neurons in the cerebellar cortex.

Detailed explanation-3: -Granule cells (neurons) are the smallest neurons in the brain. They are the only excitatory neurons in the cerebellar cortex; they release glutamate as a neurotransmitter. Axons of granule cells enter the molecular layer, bifurcate, and run along the length of a folium (parallel fibers).

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