SSC MTS EXAM

Detailed explanation-1: -Leptin is secreted mainly by white adipose tissue . Leptin levels are correlated with the amount of fat (reflecting the amount of energy stored), and with changes in caloric intake. Other factors can regulate the circulating leptin levels.

Detailed explanation-2: -It is now widely accepted that white adipose tissue (WAT) secretes a number of peptide hormones, including leptin, several cytokines, adipsin and acylation-stimulating protein (ASP), angiotensinogen, plasminogen activator inhibitor-1 (PAI-1), adiponectin, resistin etc., and also produces steroids hormones.

Detailed explanation-3: -leptin is a hormoneencoded by the ob gene and primarily secreted by white adipocytes (for reviews, see Refs. 1, 13, 14, and 38). It stimulates energy expenditure and inhibits food intake by acting via hypothalamic leptin receptors.