SSC MTS EXAM

Detailed explanation-1: -The centromere appears as a constricted region of a chromosome and plays a key role in helping the cell divide up its DNA during division (mitosis and meiosis). Specifically, it is the region where the cell’s spindle fibers attach.

Detailed explanation-2: -During metaphase, spindle fibers attach to the centromere of each pair of sister chromatids (see Figure below). The sister chromatids line up at the equator, or center, of the cell. This is also known as the metaphase plate.

Detailed explanation-3: -Kinetochore microtubules attach end-on to the kinetochore, which forms at the centromere of each duplicated chromosome. They serve to attach the chromosomes to the spindle.

Detailed explanation-4: -The two chromatids of a duplicated chromosome are held together at a region of DNA called the centromere (see figure below). Centromeres are the attachment points for microtubules, which are responsible for the guiding the movement of chromosomes during mitosis and meiosis.