SSC MTS EXAM

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SSC

BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The kinases that drive the cell cycle are actually present at a constant concentration in a growing cell, but much of the time they are inactive. To be active, kinases must be attached to a
A
centromere
B
centrosome
C
chromosome
D
cyclin
Explanation: 

Detailed explanation-1: -Cyclin-Dependent Kinases CDKs are only fully active following phosphorylation of a conserved threonine residue within the activation segment (Thr160 in the human CDK2 sequence).

Detailed explanation-2: -The activity of these kinases rises and falls as the cell progresses through the cycle. The oscillations lead directly to cyclical changes in the phosphorylation of intracellular proteins that initiate or regulate the major events of the cell cycle-DNA replication, mitosis, and cytokinesis.

Detailed explanation-3: -Cyclin-dependent kinases (CDKs) are the families of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells.

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