SSC MTS EXAM

SSC

BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the main role of Kupffer cells in a sinusoid?
A
detoxifying blood
B
producing plasma proteins
C
producing cholesterol
D
breaking down erythrocytes
Explanation: 

Detailed explanation-1: -Although their main function is phagocytosis and defence of the liver against bacteria, endotoxaemia and viral infections, they also fulfil other important roles. They will phagocytose and partially degrade bacterial antigens before handing them on to the hepatocytes for excretion into the bile.

Detailed explanation-2: -Kupffer cells are the specialized macrophages located in the liver, particularly at the lining of liver sinusoids. They are part of the mononuclear phagocyte system. Their name is derived from Karl Wilhelm von Kupffer, a German anatomist who was the first to describe them in 1876.

Detailed explanation-3: -Liver Kupffer cells rapidly remove red blood cell-derived vesicles from the circulation by scavenger receptors. Blood.

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