SSC MTS EXAM

SSC

BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the role of RNA primers, which are needed to form the lagging strand?
A
To allow RNA polymerase to bind
B
To allow DNA polymerase to bind
C
To allow DNA primase to bind
D
To allow DNA ligase to bind
Explanation: 

Detailed explanation-1: -Short fragments of RNA serve as primers that can be extended by DNA polymerase. To form a continuous lagging strand of DNA, the RNA primers must eventually be removed from the Okazaki fragments and replaced with DNA.

Detailed explanation-2: -For this reason, multiple primers need to be formed on the lagging strand so DNA polymerase can synthesize in the 5’ to 3’ direction from every primer. These fragments of DNA are called Okazaki fragments.

Detailed explanation-3: -Abstract. Primer RNA is RNA that initiates DNA synthesis. Primers are required for DNA synthesis because no known DNA polymerase is able to initiate polynucleotide synthesis. Edited transcriptional RNA is used to initiate DNA synthesis in some phage and in metazoan mitochondria.

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