BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Alanine (symbol Ala or A), or -alanine, is an -amino acid that is used in the biosynthesis of proteins. It contains an amine group and a carboxylic acid group, both attached to the central carbon atom which also carries a methyl group side chain.

Detailed explanation-2: -Alanine, Leucine, Valine, Isoleucine, Threonine and Methionine are the six natural amino acids containing methyl groups and labeling protocols have been developed for high yield production of deuterated proteins with 1H-13C methyl labeled amino acids with minimum scrambling.

Detailed explanation-3: -Alanine is a simple amino acid which has just a methyl or CH3 group as its side chain.

Detailed explanation-4: -There are three amino acids that have basic side chains at neutral pH. These are arginine (Arg), lysine (Lys), and histidine (His). Their side chains contain nitrogen and resemble ammonia, which is a base. Their pKa’s are high enough that they tend to bind protons, gaining a positive charge in the process.

Detailed explanation-5: -There are six amino acids that contain methyl groups (alanine, leucine, isoleucine, valine, threonine and methionine).