BIOMOLECULES AND ENZYMES

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BIOLOGY

AMINO ACIDS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following statements are true for Ramachandran Plot?P. it can be used to describe the backbone conformation of any polypeptide residue.Q. it can be used to describe simple secondary structures of proteins.R. it is plotted with coordinates of psi and phi of a polypeptide chain.S. it is used to describe side chain conformation of the amino acid residues in a polypeptide chain.
A
P and Q
B
P and R
C
P, Q and R
D
P, Q, R and S.
Explanation: 

Detailed explanation-1: -Ramachandran plot can be used for evaluating the accuracy of predicted protein structure.

Detailed explanation-2: -The polygly Ramachandran plot shows more allowed regions than for any other amino acid. Because gly is achiral, the sterically allowed regions are symmetric about ( = 0°, = 0°) which means that conformations with (, ) and (−, −) are identical.

Detailed explanation-3: -Peptides that are unstructured will have all the backbone dihedral angles in the. disallowed regions.

Detailed explanation-4: -Glycine has no side chain and therefore can adopt phi and psi angles in all four quadrants of the Ramachandran plot. Hence it frequently occurs in turn regions of proteins where any other residue would be sterically hindered.

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