BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Denaturation of enzymes causes bonds to be broken, structure to be disrupted and it stops functioning. This happens to enzymes when they are exposed to extreme, unsuitable conditions, for instance, high temperatures or extreme pH levels.

Detailed explanation-2: -The result is the active site’s conformation is altered and the activity of the enzyme is lost. No, a denatured enzyme cannot be renatured. The reason is that during denaturation the bonds in the enzymes are broken so the structure gets disrupted.

Detailed explanation-3: -Factors affecting enzyme activity Temperature: Raising temperature generally speeds up a reaction, and lowering temperature slows down a reaction. However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working.

Detailed explanation-4: -Denaturing enzymes If enzymes are exposed to extremes of pH or high temperatures the shape of their active site may change. If this happens then the substrate will no longer fit into the enzymes. This means the key will no longer fit the lock. We say that the enzyme has been denatured.