BIOMOLECULES AND ENZYMES

Detailed explanation-1: -However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.

Detailed explanation-2: -Changing the pH will affect the charges on the amino acid molecules. Amino acids that attracted each other may no longer be. Again, the shape of the enzyme, along with its active site, will change. Extremes of pH also denature enzymes.

Detailed explanation-3: -Enzyme denaturation occurs when an enzyme loses its native conformation, or three-dimensional structure, rendering it unable to bind to substrate and catalyze product formation. The two main causes for enzyme denaturation are deviations from optimal temperature and pH.