BIOMOLECULES AND ENZYMES

Detailed explanation-1: -The first model called the lock and key model, proposes that the shape and chemistry of the substrate are complementary to the shape and chemistry of the active site on the enzyme. This means when the substrate enters the active site, it fits perfectly, and the two binds together, forming the enzyme-substrate complex.

Detailed explanation-2: -A substrate is a single molecule, or a combination of molecules, that has a complementary shape to the enzyme’s active site. This allows the enzyme and substrate to bind together and form the enzyme–substrate complex.

Detailed explanation-3: -Only molecules with exactly the right shape will bind to the enzyme and react. These are the reactant, or substrate, molecules. The part of the enzyme to which the reactant binds is called the active site. This is a very specific shape and the most important part of the enzyme.

Detailed explanation-4: -The active site of an enzyme possesses a unique conformation (including correctly positioned bonding groups) that is complementary to the structure of the substrate, so that the enzyme and substrate molecules fit together in much the same manner as a key fits into a tumbler lock.