BIOMOLECULES AND ENZYMES

Detailed explanation-1: -In order to explain the mode of action of enzyme, Fischer proposed a Lock and Key hypothesis. According to this theory, if the right key fits in the right lock, the lock can be opened, otherwise not. Similarly, if the right enzyme fits in the right substrate, the product is formed, otherwise not.

Detailed explanation-2: -Lock and key hypothesis Enzymes are folded into complex 3D shapes that allow smaller molecules to fit into them. The place where these molecules fit is called the active site . In the lock and key hypothesis, the shape of the active site matches the shape of its substrate molecules. This makes enzymes highly specific.

Detailed explanation-3: -The lock-and-key theory of enzyme action proposes that the enzyme’s active site and the shape of the substrate molecule are complementary to one another. This allows the substrate to fit into the enzyme, like how a key would fit into a lock. If the substrate doesn’t fit, then the enzyme will not act on it.

Detailed explanation-4: -The Michaelis-Menten hypothesis.