BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Pepsin is an aspartic protease that acts in food digestion in the mammal stomach. An optimal pH of around 2 allows pepsin to operate in its natural acidic environment, while at neutral pH the protein is denatured.

Detailed explanation-2: -Pepsin, pepsin-like enzymes, chymosin, rennin, and other acid proteinases have an activity optimum at pH 2.0–3.5; papain, trypsin, chymotrypsin, and similar enzymes are most active at neutral pH (pH 6–8).

Detailed explanation-3: -Although some enzymes exhibit activity in a broad range of pH [1–3], many show maximal activity at a narrow pH range [4–6], referred to as the pH optimum.